Artificial Intelligence plays an increasingly significant role in our life. It is enabling humans to reach what was once regarded as pure sci-fi, deeply impacting all areas of development. AI systems are starting to make autonomous decisions on crucial and sensitive topics, such as self-driving cars or medical diagnosis. However, in order to use and accept them, people must be able to trust them. Such trust is built on four pillars: fairness, explainability, robustness against malicious attacks and accountability. This talk will present the challenges around the next revolution in AI: trustworthy machines.